Nucleolar targeting runs on GTP cycles
نویسندگان
چکیده
منابع مشابه
Going in GTP cycles in the nucleolus
Proteins are directed to cellular compartments by specific localization signals. A GTP-driven cycle has now been identified as a mechanism for protein targeting to the nucleolus. The involvement of a GTP switch suggests that nucleolar localization can be regulated and may be responsive to extracellular stimuli via signaling pathways. The uncovered mechanism also implies that localization is det...
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ژورنال
عنوان ژورنال: Nature Cell Biology
سال: 2005
ISSN: 1465-7392,1476-4679
DOI: 10.1038/ncb0305-217